Antifoams for Antibiotics

Antibiotics Production Antifoams

Aerobic fermentations are an important application field for the use of antifoam agents. The antibiotic producer made some changes to its manufacturing operations to accelerate the fermentation process. These changes included increasing the airflow rates into fermenter vessels increase yields and shorten processing times. However, pumping more air creates more foam, which often requires greater doses of antifoam agents to knock the foam down and keep it in check. This is especially true when using standard polyol antifoam agents like polypropylene glycol (PPG).

 

Synmac antifoam agents in the fermentation batch helped the manufacturer enhance the efficiency of downstream separation processes, resulting in less antifoam product needing to be removed during processing.